Life Extension Vitamin K2 MK-7 Low Dose 45 mcg 90 Pearls

An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone. Vitamin K is also required by calcium-regulating proteins in the arteries. Matrix Gla-protein (MGP) is a vitamin K-dependent protein, and must be carboxylated to function properly. Poor vitamin K status leads to inactive non-carboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. Since MGP is a potent inhibitor of local arterial calcification,

MGP is important in relation to the health of the entire cardiovascular system. Without enough vitamin K, calcium in the blood can bind to the arterial wall resulting in calcification. As people age, even subclinical vitamin K deficiency can pose risks to the vascular system. Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin which has been shown to be associated with increased bone loss in postmenopausal women.Vitamin K2 (menaquinones) is found in meat, eggs, and dairy products and is also found It is made by bacteria in the human intestine, providing a certain amount of the human vitamin K requirement.12 Human studies show that vitamin K2 is up to ten times more bioavailable than K1. Vitamin K2 remains biologically active in the body much longer than K1. For example, K1 is rapidly cleared by the liver within eight hours, while measurable levels of K2 (MK-7) have been detected 72 hours after ingestion.

The Rotterdam Heart Study, a large-scale, well-controlled clinical trial that followed 4,800 participants for seven years, revealed that participants who ingested the highest amounts of vitamin K2 in their diet experienced better cardiovascular fitness than people who ingested the least. 13 High intakes of vitamin K2 also corresponded to less calcium deposition in the aorta, whereas participants who ingested less K2 were more likely to show moderate or severe calcification. Animal studies suggest that ingestion of vitamin K not only blocks the progress of further calcium accumulation, but also induces a 37% regression of preformed arterial calcification.Low-dose vitamin K2 contains the menaquinone-7 form of the vitamin K2, which is not rapidly metabolized by the liver, thereby making it available to provide a more constant supply of vitamin K to the body.

• Reference737870193692
• Weight 45 gr
• Units 90 Units
• Brand Life Extension
• Product Type Supplements Vitamins

Amount Per Serving: Vitamin K2 (as menaquinone-7) 45mcg 56% Low Dose Vitamin K2 (MK-7), Other Ingredients: Medium chain triglycerides, gelatin, glycerin, purified water, carob color.